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The development of more efficacious therapies targeting endothelial inflammation and endothelialtomesenchymal transition endmt is an essential endeavor, aiming for better treatment outcomes.. Tbk1（tankbinding kinase 1）是一种重要的信号转导蛋白激酶，在免疫应答、细胞凋亡和发生等生物学过程中发挥着关键作用。 tbk1蛋白由732个氨基酸组成，属于伯氏酯酶（serinethreonine kinase）家族成员，其结构包括激酶结构域、线粒体定位信号和泛素结合结构.. The development of more efficacious therapies targeting endothelial inflammation and endothelialtomesenchymal transition endmt is an essential endeavor, aiming for better treatment outcomes.. Background atherosclerotic vascular diseases remain the leading cause of death despite the use of lipidlowering drugs..
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